Thursday, December 26, 2019
The World Is Becoming More And More Transparent Day By Day...
The world is becoming more and more transparent day-by-day through globalization since people have begun to shift their perspective, and change their way of thinking and behave accordingly. Everyone is spectating different types of cultures and the religions that other people follow across the globe, along with the mix technological advancements which will ultimately shape what people believe it to be normal or abnormal. Therefore, with the integration of what seems to be normal in todayââ¬â¢s world can be in fact abnormal a 100 years from now, and vice versa. Michael Warner illustrates in his writing, ââ¬Å"The Trouble with Normalâ⬠that, ââ¬Å"People didnââ¬â¢t sweat much over being normal until the spread of statistics in the nineteenth century. Now they are surrounded by numbers that tell them what normal is: census figures, market demographics, opinion polls, social science studies, psychological surveys, clinical tests, sales figures, trends, the ââ¬Å"mainstream, â⬠the current generation, the common man, the man on the street, the ââ¬Å"heartland of Americaâ⬠etcetera.â⬠(Warner, p.53). These are many of the few statistical perspectives that have taken great leaps through technological advancements and globalization. Similarly, we get to learn more about the human behavior through cultural and evolutionary perspectives. These methods can help guide the behavior of normality and abnormality throughout time. It seems pretty obvious from todayââ¬â¢s world that the mass migration towards the urban areasShow MoreRelatedMarketing Strategy Of Pepsico, Inc.1037 Words à |à 5 PagesIntroduction PepsiCo, Inc. was established through the merger of Pepsi-Col and Frito-Lay in 1965 and is now responsible for the selling of many soft drinks and snacks through acquisitions of Seven-Up, Pizza Hut, Taco Bell, KFC, Tropicana, Quaker Oats, and Gatorade in following years. This corporation been a forerunner of diversity and inclusion initiatives since the 1960s by appointing the first African American vice president at a major company. It has since named the first Latino cooperate officerRead MoreThe Prospects Of Melting Arctic Ice Caps And The Consequences Of Climate Change1510 Words à |à 7 Pagesprimary dangers that are capturing worldwide attention however, could this just be the tip of the iceberg for something far greater? Globalization, defined as the process of integration through interaction between individuals, corporations and governments. It is essentially impossible for a community to live and sustain itself within a vacuum; interactions through trade and foreign rela tions allow for discourse amongst nations causing mutual influences in politics, economics and culture. AlthoughRead MoreThe Causation Of The Modern Slave Trade1646 Words à |à 7 Pagessociology to the concept of human trafficking to better understand the culture behind the slave trade, including political and economic characteristics. A factor contributing to the existence of human trafficking is globalization and the development of national economies. While globalization can be beneficial for the legal aspects of the economy, it is highly dangerous to those in the slave trade. The text states, ââ¬Å"the high tech industries characteristic of the global economy depend on local infrastructuresRead MoreRoles of Information Technology in Malaysia1402 Words à |à 6 Pagescombination of computers and communication technologies. In a more common term, Information Technology is described as any technology that can help to produce, manipulate, store, and communicate. Information Techn ology are basically divided into two parts which are computer technology and communication technology. Information Technology has brought the world into the era of globalization. More over, it has not only brought people around the world closer together, but it has also allowed the worlds economyRead MoreGlobalization And Westernization1532 Words à |à 7 PagesThe rise of the western world and capitalism has given shape to the worldsââ¬â¢ economy, politics, and culture, forever changing the way of human society. Business became an integral part of society, providing goods and services to those who could otherwise not be able to obtain them. Businesses interests over the years has spurred innovation and progress. But it would be irresponsible to believe that all business is good. Over the course of history there have been myriad examples of corporations manipulatingRead MoreReasons for the Increasing Importance of Corporate Governance and Benefits of Good Corporate Governance1262 Words à |à 6 Pagescontrolling and directing the companies. Corporate governance is not a new con cept but it has got popularity in the last few decades due to various crises such as: East Asian crisis of the late 1990s and various other fraudulent activities in the corporate world. Amongst the major reasons for the increasing interest in corporate governance are the following needs; Need for Stability of Stock Prices Stability of stock prices is one of the important factors for the investors to predict the future performanceRead MoreThe And Its Impact On Society1707 Words à |à 7 Pages1. Zakaria argues that societies are going through democratization where closed systems are becoming more open. Therefore, now social change is originating from the masses unlike in the past. Today democracy is not just a form of government it is a way of life. For example, a singer that is more popular is also more successful. Large groups of people are what create change. Even capitalism is becoming more democratic. 2. Zakaria defines constitutional liberalism as the goals of government suchRead MorePros And Cons Of Telecom Industry1231 Words à |à 5 Pages Indian Telecom Sector: Pros Cons of Merger and Acquisition for different players of Telecom Sector 1. Introduction: 1.1 Indian Telecom Sector Day by day telecommunication are becoming the essential necessity for people of India .During the liberalisation in 1990ââ¬â¢s Indian Telecom industry came out from monopoly of Government of India, then after with the entry of private operators and initiation of FDI Indian telecom industry has shown tremendous growth Figure-1 Positioning of differentRead MoreSwot Analysis : Counterintelligence ( Ci )1554 Words à |à 7 Pagesmeasures may diminish confidence in the final results (Van Cleave, 2013). According to Federal Bureau of Investigation (2011) after the 9/11 attacks, ââ¬Å"significant advances have been made in clarifying and rectifying intelligence gaps and requirements through the formation of liaison and working relationships with other U.S. intelligence community agencies, foreign partners, the private sector, and academiaâ⬠. For instance, since 2001, FBI CI program has resulted in total arrests of 249, of which 46 ofRead MoreInculcate Ethical Values in Children to Protect the Nation from the Depleting Morals and Ethical Values Under the Shade of Globalization2378 Words à |à 10 PagesWays and Means to inculcate Ethical Values in the children to protect the nation from the depleting morals and ethical values under the shade of Globalization `Children are our most valuable natural resource. -Herbert Hoover ââ¬Å"India will be radiant when our children are free to dance in the rain- Azim H Premji, Chairman Wipro. ââ¬Å"It is necessary that steps are taken to properly nurture them in the right direction at an early age, says Sriram Kannan. Introduction Ethical values generally refer to
Tuesday, December 17, 2019
Cell Phone Use While Driving - 1503 Words
ââ¬Å"Imagine traveling on the roadway behind a vehicle swerving back and forth over the lines or driving at very inconsistent speeds. You wonder what could possibly be causing the driver to drive so erratically. Is the driver drunk? Is the driver preoccupied with eating his or her lunch? Is the driver busy attending children in the backseat? Once you pull along the side you realize that was not the case, instead you notice the driver has a cellular telephone up to her or his ear chatting away, or even worse you pass and see the driver holding a phone texting, you pass by and you feel so discussed.â⬠(Noder, Shannon L., 2010) Cell phones are among the most popular electronic devices used in the US, especially while conducting a motor vehicle. Cell phone use while driving has become very popular among the past years; we hear about it more frequently, do you know what can happen to you when you use an electronic device while driving? Cellphone use while driving may include, textin g phone calls, gps and networking, those are all actions done while driving, this should be stopped, cell phone use while driving should be banned in the US. An effort to increase overall roadway safety continues to rise as the number of motor vehicle inquires and fatalities of car crashes continue. As the roadway danger of cell phone use while driving continue to rise there are less and effective policies to deter their use while behind the wheel. Cellphone use while driving also producesShow MoreRelatedUse Of Cell Phones While Driving860 Words à |à 4 PagesAmericans rely heavily on cell phones to perform daily activities. Cell phone are used for phone calls, email, sending text messages, surfing the internet, and performing other tasks. It is unfortunate that many of these daily activities occur while a person is driving. As a result, an increase of accidents and fatalities have occurred because of the use of cellular phones while driving. Using a cell phone while driving is an epidemic that has taken our nation by storm. Most drivers believe theyRead MoreCell Phone Use While Driving990 Words à |à 4 Pages Cell phones are integral to peopleââ¬â¢s lives in Canada because they are vital communication and entertainment tools. However, the use of cell phones has remained contentious, because texting and talking on the phone are associated with distracted driving. Distracted driving is, ââ¬Å"defined as the diversion of attention away from activities critical for safe driving toward a competing activityâ⬠(Klauer, Guo, Simons-Morton, Ouimet, Lee Dingus, 2013, p. 55). Although distracted driving is also associatedRead MoreCell Phone Use While Driving1114 Words à |à 5 PagesToday, we use our cell phones for just about anything and everything to include; texting, talking to our loved ones, and connecting with the rest of the world via social media. Cell phones have become a natural way of life to where we pick up our phones and use them like second nature. However, the dangers present themselves when we get behind the wheel of a car and carry these habits of cell phone addictions with us. If all states ban the use of cell phones while driving, then there would be a reducedRead MoreThe Use Of Cell Phones While Driving1817 Words à |à 8 Pagesknowledge that the use of cell phones while driving decreases driver awareness and overall road safety, and in response to this knowledge, some states have passed laws that have prohibited the use of handheld devices. However, there are no laws banning hands free cell phone usage, despite research claiming hands free devices are just as dangerous handheld devices. But, does their usage distract drivers enough to the point where states should legally ban the total use cell phones while driving? The followingRead MoreUse of Cell Phones While Driving824 Words à |à 4 PagesIf you are driving at 55mph for 5 seconds in that amount of time you could cros s a football field. People donââ¬â¢t understand how dangerous distracted driving really is. All states should have some sort of legal parameters of what happens when you get caught using your cell phone while driving. People should get a stronger/ harsher punishment for the use of a cellular device while driving. People are way more impaired when you are distracted and driving than you are drinking and driving. The problemRead MoreThe Use Of Cell Phones While Driving1843 Words à |à 8 Pagesknown that the use of cell phones while driving decreases driver awareness and overall road safety, and in response to this knowledge, some states have passed laws that have prohibited the use of handheld devices. However, there are no laws banning hands free cell phone usage, despite research claiming hands free devices are just as dangerous handheld devices, but does their usage distract drivers enough to the point where states should legally ban the total use cell phones while driving? The followingRead MoreThe Use Of Cell Phones While Driving1509 Words à |à 7 PagesSeveral states have enacted laws banning the use of cell phones while driving; an indication of the type of society America has become. These laws were put in place not only to keep drivers from taking phone calls, but also to deter them from posting their latest tweet or commenting on their friendââ¬â¢s latest picture. Social medi a is so ingrained in society today that many are unable to entertain a world that is devoid of such technology. With usage at an all-time high, the psychological effects ofRead MoreCell Phone Use While Driving Essay1816 Words à |à 8 PagesThe study was attempting to determine the thoughts and behaviors that African American freshman college students in regards to cellphone use while driving. They wanted to know how the students thought cellphones (independent variable) impact driving skills (dependent variable). Research suggests that cellphone use correlates to higher likelihood of accidents. The study used 331 (195 females and 136 males) freshman students who held a driverââ¬â¢s license. The students were then given a questionnaireRead More Cell Phones And Driving: Dangers Involved with Cell Phone Use While Driving1036 Words à |à 5 Pagesoften. Talking on the cell phone and driving has become a very popular thing these days. Technology is coming out with the newest phone s that can do everything for you and people are attracted to that. There are people that donââ¬â¢t have hands free and drive their car with only one hand, people that text and totally take their eye off the road and type conversations to each other. Bluetooth is another technological breakthrough where you wear an ear piece and can receive phone calls by one touch ofRead MoreStop the Use of Cell Phones While Driving854 Words à |à 4 Pages13 2013 Many people driving donââ¬â¢t know that they can be so many wrongs they can be doing without realizing it. Plenty talk on the phone while driving, drink, text and drive. A lot of people even innocent people as well have had accidents involving one of those. Out of the three there has been one that has become more common, and itââ¬â¢s only increasing if people donââ¬â¢t put a stop to it themselves. A usage of a cell phone should not be displayed at any point while driving. It can wait many have had
Monday, December 9, 2019
Support For Health And Disease In Communities
LO 1. Understand different approaches and strategies used to measure, monitor and control the incidence of disease in communities 1.1. Explain the roles of different agencies in identifying levels of health and disease in communities Health restoration and health management are two crucial concepts, which decides the healthy state of any community. With respect to the diverse habitat of human being, the spread of population is vast throughout the globe, which fetch diversity in food, life style, culture and other specific traits. Likewise, the variation in health state of the diverse people is different, where at one place is affected with tropical neglected disease and at another part it is affected by the poverty state. It is hence, the placement of various agencies in each nation, in each state, in each district and each location is important. The functionality of these agencies, lies in context of understanding the health issues with in the locality, find suitable causes behind it, collect data relative to prevalence, occurrence and pandemic state, share the health concern with the agencies at higher level, and thereby translate the knowledge related to health issues and subsequent solution (WHO, 1980). In ot her words, it can be said that the functionality of various agencies lies in context to build partnership model with the community member, with government and non-government agencies, with international agencies for the wellbeing of the community and sustaining the prosperity of healthy state. The role of various agencies in concern to health and disease also lies with respect to the governing the establishment of health and social care settings, their functioning roles, the competency of health care professionals by regulating their education system, training module, criteria for licensing and monitoring the workflow. On local, national and international level, these agencies are responsible for framing effective guidelines for the health restoration as well as management with the help of public policies, ethical cum legislative framework and making various amendments for the wellbeing of the society. Similar is the monitoring of the expenditure in terms of health management issues with respect to per capita income and GDP of the nation. Thus, the focus is related to meet the challenge of health gap for any community with respect to the corresponding health expectancies (Brandt Rozin, 2013). 1.2. Explain, using statistical data, the epidemiology of one infectious and one non-infectious disease that is widespread in their own country With respect to the discussion theme, it would be more suitable to focus on any agency that is functional on the worldwide scale. In conjunction to the said concept, World health Organization (WHO) is more suitable compared for the concern of discussion of health and disease issue. Likewise, it is important to note that the epidemiological concern, prevalence and occurrence and the corresponding statistical cum quantitative term is more important in context to global burden of disease (GBD) concept (John, 2011, pp.252). With respect to the health and disease concern, the concept of DALY (a summative measure of population health) is more suitable which in numerical or statistical term is represented as summation of YLL and YLD (Equation 1). Equation 1 Where YLL is years of life lost due to premature mortality and YLD is years lived with disability. This mortality at premature state or disability state, where the physiological conditions and corresponding state of mind is not in good state can be correlated with respect to infection and non-infection state. Notably the statistical terms for the same concern is always derived by classifying the data in terms of age, sex and geographical region. The key estimate of the health and disease issues are used to estimate routinely with respect to the incidences and point prevalence of the disease. These studies are carried out with respect to infection diseases such as HIV/AIDS, tuberculosis, malaria, sleeping sickness, leishmaniasis and other related infection. Similarly, in case of non-infection diseases that same concern is expressed with respect to Alzheimer disease, Astham, Diabetes mellitus, Parkinson disease, heart failure, cancer and related disorder. In brief the statistical assumption of the disability states with respect to diseases is calculated by equation 1:: Equation 2 Where I is number of incident cases, DW is the disability weight and L is the average duration of disability in years. It is noteworthy to mention that the application of equation 2 is executed without taking into the consideration of social preference or cultural attributes, and fetch the significance of prevalence and occurrence with respect to disabling event (Pullan, 2012, pp.1870). 1.3. Evaluate the effectiveness of different approaches and strategies to control the incidence of disease in communities The prime notation in conjunction to various approach and strategies for the control of any incidence and disease in a community is based on the assessment and identification of associated links. It is hence the identification of specific traits, its occurrence, the possible cause and the implementation measures are important in this regard. Apart from the basic requirement of infrastructure, facility and workforce in terms of health care professionals, for any region, it is also important to understand the specific traits existing in the location. These traits are related to the social and cultural influences, the religious believe and the environment associated within it. Thus, for the purpose of effective health restoration, it is important for the policy maker, for the health care professionals and the community individual itself to take care of these issues. The next approach is the understanding and acquiring of the knowledge related to diverse health concerns that are incorpor ated in the health pattern of any community. The estimates of these health patterns in general are derived by the agencies responsible for the same. Example of the functioning mechanism was explained in above section like DALY (Patel, 2011, pp.413). An effective strategy is concerned with the competency of the concerned health care professionals. This ensure that the adoption of the intervention method and the treatment regime is suitable for the concerned health issues. In particular the strategies adopted for the health restoration and health management lies in five crucial steps. (i) assessment and identification of the associated risk and concerned risk; (ii) planning the treatment regime and effective management for the concerned problem, (iii) identification of any crucial change and implementation for making the health restoration process effective (iv) monitoring the progress of the implemented approach and (v) sustaining the effective measure by educating and concerned on the self-management of the disease. Notably, with the adopted for the said points, it is equally important to take care of the ethical and legislative concerned imposed by the guidelines and regulatory framework by the local, national and international agencies. Adopted of such concern in practice will ensure minimum enclose for risk and also ensure maximum positive benefit against the adopted strategy (Di Cesare, 2013, pp.585). LO 2. Be able to investigate the implications of illness and disease in communities for the provision of health and social care services 2.1 Use relevant research to determine current priorities and approaches to the provision of services for people with disease or illness Current policy priority matters and assessment for the health needs are important tool for the identification, recognition and making appropriate planning of health care to meet the demands and convey the necessary implementation. These approaches not only ensure the wellbeing of the society but also work for the sustainability of the health care standards in the community. The essential tool in this regard is the building and maintenance of effective partnership model among the various health care professionals as well as in conjunction to the concerned community members. They points to be considered in this context of epidemiology and defining the health service needs are related to following assumptions (Maher, 2012, pp.1): Understand the need, demands and corresponding use of the requisite planning and services. Defining the assessment and requisite needs for the health concern of the community. Identification and implementation of appropriate approaches for the assessment of health needs. Framing an effective framework for the health need assessment. Professional judgment, recognition and realization of the need and comparative assessment in this conjunction is valuable and worthy. These approach are helpful for analysis of both the clinical activities and associated cost benefit analysis. Other factors which are involved in this concern are related to illness behavior in the community with respect to age, gender, socio-economic class and education. The illustration of the concerned approach and strategy for health and social care is thus framed on the basis of statistical factors, demand factor of health care services and supply factors for the requisite service and care plan. It is noteworthy to mention that the service related activities and utilization are crucial for the framing and implementation of the strategies. These utilization are decided on the basis of either (i) service based utilization, for example the bed occupancy, number of available health care professionals per bed and (ii) population based activity such as immunization coverage and prescription. The reflection of the effectiveness in strategies can be obtained with inverse law, where the increase in effective of services will leads to reduction in the hospital admission and mortality cum morbidity rate (Atrash Carpenter, 2012, PP.396). 2.2 Explain the relationship between the prevalence of disease and requirements of services to support individuals within the health and social care service provision According to the definition of WHO, health can be defined as a complete state of physical, mental and social wellbeing. It is hence the absence of diseases or disorders does not confirm the healthy state of individual. The relationship between the prevalence of disease and the corresponding requirement of the services can be summaries in following points, viz (Maron, 2014, pp.1303; Haas, 2013, ppS100): Identification of the public interest, which depicts not only the requisite parameters for the wellbeing state of health, but is also related to identification and assessment of the health concern related to any outburst of infection or disorder. Assessing the health priorities, which involve collection of both qualitative and quantitative data. These data on the other hand reflect the extent of the need for health related services. Notably the availability of the information and skills in the health care professionals are also included in this context. Identification of issues that is most important in comparison to all the existing priorities for action. The factors, which are helpful in this regard, are size and severity of the health concern, availability of the services, efficiency and effectiveness of the services and partnership arrangement. Implementation and monitoring of the change program in the community. This helps in ensuring that the measures adopted are effective and are potent enough to produce positive results. The concept of health economics is important to understand and make into existence in the real life scenario. It is the government agencies, which are responsible for the incorporation and application of revenue for the services in the community health needs. These strategies include the investment of capital in terms of per capita income and per GDP. The efforts of this kind helps in managing the number of beds in the community and the corresponding workforce required per bed to meet the diverse health and social care related needs. 2.3 Analyze the impact of current lifestyle choices on future needs for health and social care services The current life style choice seeks for more comfort and less activity in developed and developing countries. These lead to state of increase in cases for obesity, diabetes, congestive heart failure and other related disorders. Likewise, in underdeveloped countries and tropical states the concern is mainly focused on parasitic diseases such as Leishmania, tse-tse fly, malaria, cholera and tuberculosis. It is hence, when the overall scenario of the world health prospect is visualized, there are diverse problems and concerns, which are acting as barrier for the wellbeing of the society (Marmot, 2012, pp.1011). The effectiveness in the measure can be increased with increased sharing of the knowledge, emphasizing over the health issues and physiological need. The generalized need of the awareness are with respect to food and diet precautions, avoidance of the addictive elements such as alcohol, nicotine and cocaine. Other education and awareness are in conjunction to health aspects of women and children, safe sex, education, hygiene and cleanliness. These measures will help in better generalization related to health restoration and health management. Looking on to the other part of development, related to the advancement of science and technology and the advancement in medical science, there are improvement and amendment in the ethical and legislative concerns. Similarly, with time there is an increased development of nursing theories, increased adopted of borrowed theories for the nursing and related health care practices. Increase in the concern of training and education is helpful in this regard, as it works for acquisition of better competency level of the health care practitioners. The raised concern of both government and non-government agencies have opened wide option of similar medical facilities irrespective of the geographical location (rural and urban), more practical usage of telenursing, increase in video consulting among the health care professionals. All these measures are ultimately running with single objective, that is the improvement of patient outcome (Blank, 2013). LO 3. Understand the factors influencing health and wellbeing of individuals in health or social care settings 3.1 Assess the health and wellbeing priorities for individuals in a particular health or social care setting Health inequality is the basic concern for the assess of the services and care in any health care settings. Public priorities and practice guidelines by the health care settings, should have the approach for explicit addressing of the inequalities in all the department and level. Often these inequalities were developed with respect to the socioeconomic class, cultural, ethnical and language, age, gender and other similar characteristics. The next factor, which can modulate the available health care services and the corresponding demand of the services are related to health promotion and prevention strategies (Kieling, 2011, pp.1515). The proverb prevention is better than cure, is applicable to many ill conditions such as infection, addiction and abuse. Increase in the investment for the health care services with respect to the instrument, medication, research and competencies of health care professionals should be accompanied with raising the awareness among the community members. Th is is possible with the help of displaying information on the websites, patient centered counseling and educating the family members and carer of the patient. Example of some specific areas, where the increase in awareness can be helpful are smoking, obesity, safe sex, breast feeding, physical activity, risky activities adopted by young, poverty and education. To the next, the use of effective communication skills by the professionals is also crucial in addressing the health priorities issues and related services in any health care settings. These skills are important in both verbal and non-verbal communication. Notably the use of effective communication skills is worthy among both multidisciplinary professionals as well as among the health care professionals and patients. Importantly, this also have another advantage of building effective partnership model for the facilitation of health care services in the community. translation of the health related information and implementing effective care plan are beneficial as a part of effective health restoration approach (Salomon, 2013, pp.2129). 3.2 Evaluate the effectiveness of strategies, systems and policies in a health or social care setting The effectiveness of any strategy lies in context to change management and implementation of care plan. The strategies, systems and policies in the health and social care is always governed with in conjunction to the guidelines and policies. Some of the major work in this regard can be highlighted in the below mentioned rebuttal points (Grol, 2013): Focus on the financial resources and availability of the revenue, that can be made into use for building and applicability of the health services. Systematic involvement of the community members and experts from the field of health sector in designing and delivery of services. Focusing on the partnership models among the various professionals of the health care settings, which will help in providing integrated services for the care system. Apart from the said measures, other parameters, which are crucial for the evaluation of effectiveness can be made in concern of training and education. A fine concern of training and education system of health care, can be reflected with respect to the improved health condition of the community. For instance the reduction in mortality, morbidity and less occurrence of hospital readmission is the reflection of effective training and education. Concisely this also leads to increased patient satisfaction against the health care services (Schwarlander, 2011, pp.2031). 3.3 Discuss changes that could be made to improve the health and wellbeing of individuals in a health or social care setting The changes can be made by ensuring that the related services are assessed in accordance to the needs and targets. Such approach will be helpful for fulfilling the existing gap between needs and available services. Demonstrating how health inequalities are made for compensating the designed services are also included within the same scope of improvement. Knowledge and adoption of appropriate competencies have the most positive impact over the better health prospect. It is noteworthy to mention that within the increase in globalization and mix cultural habitants, it is important for the health care professionals to pay attention towards diverse cultural and ethical difference. The improvement of the services should be concurrent according to the advance in science and technology. Reflection of the improvement in the health care services can be enhanced only with the health status of a healthy city (Marmot, 2012, pp.1011). Risk identification and assessment of the health concerns in important for all the health care settings. Such approach not only reduces the probability of ills effects, but will also ensure that there are less errors in the health care practices. Record making and storage is also important aspect, which is needed to be in correct track for the sustainability of health care standards. This include important part such as safe recording, easy retrieval, and convenient sharing (Mechanic, 2012, pp.376). 3.4 Evaluate an activity that has been implemented to encourage behavior change for maximizing health for individuals in a health or social care setting One of the main concerns in the health care settings is the management of change. The process is somewhat tricky as it involves a complicated process in which the health care professionals sometime support it, sometimes obligate to it, remain indifferent to it, and be passive or active to the changed scenario. In other words, it can be said that the management of any change within the health care settings involved several steps of evaluation, planning, implementation, strategies, guidelines and policies, which should ultimately focus on effective patient outcome (Klasnja, 2011, pp.3063). It would be genuine to argue that the change associated in a dynamic health care system is not only a choice in-between health care consumers demand and technological advancement, but is a combined solution of all the issues raised from combination of these two attributes. The example of implementation for the scope of present discussion can be related to the food support program, made effective by WHO (Gordon, 2011, pp.359). The key effect can be observed with respect to improvement in maternal and perinatal outcomes. It is important to note that the significance of such work is related to low birth weight, pre-term birth and similar perinatal outcomes, which becomes favorable. Other than this, it also improves the ill health condition of the women such as gestational diabetes, depression and anemic conditions. In short, it can be said that the impact of such implementation was over the birth rate and health aspects of the mother. References: ATRASH, K., CARPENTIER, R. 2012. The evolving role of public health in the delivery of health care. Revista brasileira de crescimento e desenvolvimento humano, 22(3), 396-399. BLANK, R. A. 2013. The price of life: the future of American health care. Columbia University Press. BRANDT, A. M., ROZIN, P. (Eds.). 2013. Morality and health. Routledge. DI CESARE, M., KHANG, Y. H., ASARIA, P., BLAKELY, T., COWAN, M. J., FARZADFAR, F., ... EZZATI, M. 2013. Inequalities in non-communicable diseases and effective responses. The Lancet, 381(9866), 585-597. GORDON, R. A., KAESTNER, R., KORENMAN, S., ABNER, K. 2011. The Child and Adult Care Food Program: Who Is Served and Why?. Social Service Review, 85(3), 359-400. GROL, R., WENSING, M., ECCLES, M., DAVIS, D. (Eds.). 2013. Improving patient care: the implementation of change in health care. John Wiley Sons. HAAS, L., MARYNIUK, M., BECK, J., COX, C. E., DUKER, P., EDWARDS, L., ... YOUSSEF, G. 2013. National standards for diabetes self-management education and support. Diabetes Care, 36(Supplement 1), S100-S108. JOHN, T. J., DANDONA, L., SHARMA, V. P., KAKKAR, M. 2011. Continuing challenge of infectious diseases in India. The Lancet, 377(9761), 252-269. KIELING, C., BAKER-HENNINGHAM, H., BELFER, M., CONTI, G., ERTEM, I., OMIGBODUN, O., ... RAHMAN, A. 2011. Child and adolescent mental health worldwide: evidence for action. The Lancet, 378(9801), 1515-1525. KLASNJA, P., CONSOLVO, S., PRATT, W. 2011. How to evaluate technologies for health behavior change in HCI research. In Proceedings of the SIGCHI Conference on Human Factors in Computing Systems (pp. 3063-3072). ACM. MAHER, D., FORD, N., UNWIN, N., FRONTIRES, M. S. 2012. Priorities for developing countries in the global response to non-communicable diseases. Globalization and health, 8(1), 1-8. MARMOT, M., ALLEN, J., BELL, R., BLOOMER, E., GOLDBLATT, P. 2012. WHO European review of social determinants of health and the health divide. The Lancet, 380(9846), 1011-1029. MARON, B. J., FRIEDMAN, R. A., KLIGFIELD, P., LEVINE, B. D., VISKIN, S., CHAITMAN, B. R., ... THOMPSON, P. D. 2014. Assessment of the 12-Lead ECG as a Screening Test for Detection of Cardiovascular Disease in Healthy General Populations of Young People (1225 Years of Age) A Scientific Statement From the American Heart Association and the American College of Cardiology. Circulation, 130(15), 1303-1334. MECHANIC, D. 2012. Seizing opportunities under the Affordable Care Act for transforming the mental and behavioral health system. Health Affairs, 31(2), 376-382. PATEL, V., CHATTERJI, S., CHISHOLM, D., EBRAHIM, S., GOPALAKRISHNA, G., MATHERS, C., ... REDDY, K. S. 2011. Chronic diseases and injuries in India. The Lancet, 377(9763), 413-428. PULLAN, R. L., STURROCK, H. J., SOARES MAGALHAES, R. J., CLEMENTS, A. C., BROOKER, S. J. 2012. Spatial parasite ecology and epidemiology: a review of methods and applications. Parasitology, 139(14), 1870-1887. SALOMON, J. A., VOS, T., HOGAN, D. R., GAGNON, M., NAGHAVI, M., MOKDAD, A., ... FLOOD, L. 2013. Common values in assessing health outcomes from disease and injury: disability weights measurement study for the Global Burden of Disease Study 2010. The Lancet, 380(9859), 2129-2143. SCHWARTLNDER, B., STOVER, J., HALLETT, T., ATUN, R., AVILA, C., GOUWS, E., ... PADIAN, N. 2011. Towards an improved investment approach for an effective response to HIV/AIDS. The Lancet, 377(9782), 2031-2041. WORLD HEALTH ORGANIZATION. 1980. International classification of impairments, disabilities, and handicaps: a manual of classification relating to the consequences of disease, published in accordance with resolution WHA29. 35 of the Twenty-ninth World Health Assembly, May 1976.
Monday, December 2, 2019
Writings Of Thomas Hobbes And J.J.C. Smart Essay Example For Students
Writings Of Thomas Hobbes And J.J.C. Smart Essay Surpassing the Obvious:Analysis of the Writings of Thomas Hobbes and J.J.C. Smart A term paper contrived is only as good as the sources from which it is assembled. It is from these reservoirs of knowledge that the bulk of a paper is developed. That is why it is absolutely imperative that the qualities of these sources are immaculate and relevant to the subject matter. Given my subject matter, ethical obligations and violence, it is critical to note and record the viewpoint of different philosophical ethical theories through the writings of different philosophers. Excerpts form Thomas Hobbes The Leviathan and J.J.C. Smart in Ethics for the Modern Life, prove to be effective in both previously matriculated qualities. Both authors give arguments for different types of ethical theories that give some aspect of significant worth to my term paper topic. We will write a custom essay on Writings Of Thomas Hobbes And J.J.C. Smart specifically for you for only $16.38 $13.9/page Order now In The Leviathan, Thomas Hobbes argues from a modified psychological egoist stand. By this it is meant that in his writings he argues that every one has a strong intrinsically engrained psychological tendency to act selfishly and that it takes hard work and individual sacrifice to obtain any type of altruistic goal. Hobbes argues that man is naturally in a state of nature and within this state each man is at constant war with other men in order to take and maintain property. He argues that it is our natural right that is derived from our helpless selfishness that causes this environment of destruction and constant fear. The reason that Hobbes is separated away from other psychological egoist is in his belief that man has as opportunity to ascend out of the barbarous state of nature to a higher plane of security and society. According to Hobbes this can only happen when the aforementioned natural right to everyone elses property is relinquished by all to an ultimate sovereign: the Lev iathan. Given that this right is renounced by all the element of fear is eliminated. Hobbes states that through the leviathan all concepts will be settled with a fair hand. J.J.C. Smart, however, does not go into such detail into the psyche of man as a whole; rather his objectives center around an ethical theory that he feels all men should accept and participate in. This theory is rule-utilitarianism. Being a subset of simple utilitarianism its goals are synonymous with strict utilitarianism in that its ultimate intent is to provide the greatest happiness to the greatest number. Rule-utilitarianism, nevertheless, does provide for a more specific stipulation than simple utilitarianism. It states that any act is right (or ethical) if that act provides the most happiness to the most people. Smart argues that under Rule utilitarianism basic moral principles (i.e. dont steal, dont lie) are simply non-existent. This is because in some situations it may cause more happiness to lie and in those scenarios there should be no reservations in lying. Thomas Hobbes effectively and persuasively argues for his beliefs in his book, The Leviathan. His strength in his convictions solidifies his arguments to audiences of both high expertise and those with less formal education in the subject. Thomas Hobbes, being a renowned philosopher, brings with his book a very high respect from philosophers of every kind. This reputation is another positive attribute that sets Hobbes apart from the crowd and consequently makes his work a verifiably good source. Ironically, the age of this writing acts as a positive characteristic in its reputability as a good source. Although its first publication was in 1651, there have been few, if any deviations to his ideology. Hobbes, being a philosopher before his time, became a forerunner and set the standard by which most modern philosophers follow. J.J.C. Smart also expostulates effectively. In his arguments he is clear and concise and steers away from the pompous tone that philosophers sometimes enlist tha t causes the reading to be dull. His grounds also seem to be rooted in a great amount of his individual belief in his subject matter. Smart is extremely capable of displaying his passion for his thesis through his writing. Although not as well known as Thomas Hobbes, Smart does have a worthy reputation within the realms of philosophy. Conversely to Hobbes, Smarts work was published at a significantly more recent time. Similar to Hobbes, Smarts thesis remains relevant throughout time. Given that it relates a philosophical view, it does not become irrelevant with time. Therefore his writings will always be current in the respect that they are pertinent to what is relevant in the world community. .u4e98e4c28b40dac0306a7664750c0843 , .u4e98e4c28b40dac0306a7664750c0843 .postImageUrl , .u4e98e4c28b40dac0306a7664750c0843 .centered-text-area { min-height: 80px; position: relative; } .u4e98e4c28b40dac0306a7664750c0843 , .u4e98e4c28b40dac0306a7664750c0843:hover , .u4e98e4c28b40dac0306a7664750c0843:visited , .u4e98e4c28b40dac0306a7664750c0843:active { border:0!important; } .u4e98e4c28b40dac0306a7664750c0843 .clearfix:after { content: ""; display: table; clear: both; } .u4e98e4c28b40dac0306a7664750c0843 { display: block; transition: background-color 250ms; webkit-transition: background-color 250ms; width: 100%; opacity: 1; transition: opacity 250ms; webkit-transition: opacity 250ms; background-color: #95A5A6; } .u4e98e4c28b40dac0306a7664750c0843:active , .u4e98e4c28b40dac0306a7664750c0843:hover { opacity: 1; transition: opacity 250ms; webkit-transition: opacity 250ms; background-color: #2C3E50; } .u4e98e4c28b40dac0306a7664750c0843 .centered-text-area { width: 100%; position: relative ; } .u4e98e4c28b40dac0306a7664750c0843 .ctaText { border-bottom: 0 solid #fff; color: #2980B9; font-size: 16px; font-weight: bold; margin: 0; padding: 0; text-decoration: underline; } .u4e98e4c28b40dac0306a7664750c0843 .postTitle { color: #FFFFFF; font-size: 16px; font-weight: 600; margin: 0; padding: 0; width: 100%; } .u4e98e4c28b40dac0306a7664750c0843 .ctaButton { background-color: #7F8C8D!important; color: #2980B9; border: none; border-radius: 3px; box-shadow: none; font-size: 14px; font-weight: bold; line-height: 26px; moz-border-radius: 3px; text-align: center; text-decoration: none; text-shadow: none; width: 80px; min-height: 80px; background: url(https://artscolumbia.org/wp-content/plugins/intelly-related-posts/assets/images/simple-arrow.png)no-repeat; position: absolute; right: 0; top: 0; } .u4e98e4c28b40dac0306a7664750c0843:hover .ctaButton { background-color: #34495E!important; } .u4e98e4c28b40dac0306a7664750c0843 .centered-text { display: table; height: 80px; padding-left : 18px; top: 0; } .u4e98e4c28b40dac0306a7664750c0843 .u4e98e4c28b40dac0306a7664750c0843-content { display: table-cell; margin: 0; padding: 0; padding-right: 108px; position: relative; vertical-align: middle; width: 100%; } .u4e98e4c28b40dac0306a7664750c0843:after { content: ""; display: block; clear: both; } READ: DRUG ABUSE EssayProbably the strongest argument against Hobbes the Leviathan, is the argument against psychological egoism itself. The basic concept of psychological egoism is that all acts done by man are selfish in nature. This viewpoint is unverifiable in that any contention against it can be disputed away by the simple argument that whether man believes it or not his subconscious drives him to be selfish in all of his endeavors. Since their can be no argument against the unknown motives of the subconscious mind, Hobbes stands without strong opposition, which does not make for a good source. Another weakness, though not as egregious as the first is this sources distance in theme to the topic. There is in no part where Hobbes argues on the ethical obligation and violence. However, his arguments can very easily be analyzed and connected to the thesis of my term paper. Smart, although not without opposition as Hobbes appears to be, does not give a spot in his writing to the common opposition that utilitarian views sometimes receive. He fails to identify and argue away these counter-arguments and subsequently weakens his points. Likewise as with Hobbes writing, there is no point in which Smart discusses the specific points of ethical obligation and violence. However, similar to Hobbes, Smarts arguments can easily be transcribed and made relevant to the theme of the term. Hobbes and Smart, both well-known and respected philosophers and writers, produce the ultimate examples of good sources. It is in their writing that any scholarly researcher searching for anything philosophical in nature can find a reliable, complete derivation of knowledge. As stated before these publications are relevant to my term paper in a much more involved way than the superficial. It is the underlying beliefs in each one of these philosophers viewpoints that provides me with a strong foundation to build my thesis on and subsequently my term paper. English Essays
Wednesday, November 27, 2019
Definition of Aggregate Demand
Definition of Aggregate Demand Definition: Aggregate demand is the sum of all demand in an economy. This can be computed by adding the expenditure on consumer goods and services, investment, and net exports (total exports minus total imports). Terms related to Aggregate Demand: DemandSpeculative DemandAggregate Supply About.Com Resources on Aggregate Demand: Aggregate Demand Aggregate Supply Practice QuestionCost-Push Inflation vs. Demand-Pull InflationSupply Shocks, Demand Shocks and the AD/AS Model Writing a Term Paper? Here are a few starting points for research on Aggregate Demand: Books on Aggregate Demand: Aggregate Demand and MacRoeconomic Imbalances in Thailand: Simulations With the Siam 1 ModelThe Federal Reserves response to aggregate demand and aggregate supply shocksAggregate Demand, Productivity, and Disguised Unemployment in the Chinese Industrial Sector Journal Articles on Aggregate Demand: The Dynamic Effects of Aggregate Demand and Supply DisturbancesCredit, Money, and Aggregate DemandAggregate Demand Management in Search Equilibrium
Saturday, November 23, 2019
Hittites and the Hittite Empire
Hittites and the Hittite Empire Two different types of Hittites are mentioned in the Hebrew Bible (or Old Testament): the Canaanites, who were enslaved by Solomon; and the Neo-Hittites, Hittite kings of northern Syria who traded with Solomon. The events related in the Old Testament occurred in the 6th century BC, well after the glory days of the Hittite Empire.The discovery of the Hittite capital city of Hattusha was an important event in archaeology of the near east, because it increased our understanding of the Hittite Empire as a powerful, sophisticated civilization of the 13th through 17th centuries BC. The Hittite Civilization cuneiform à Timeline Old Hittite Kingdom [ca. 1600-1400 BC]Middle Kingdom [ca. 1400-1343 BC]Hittite Empire [1343-1200 BC] Babylon Sources Cities: Important Hittite cities include Hattusha (now called Boghazkhoy), Carchemish (now Jerablus), Kussara or Kushshar (which has not been relocated), and Kanis. (now Kultepe)
Thursday, November 21, 2019
English Legal System, Coursework Essay Example | Topics and Well Written Essays - 1750 words
English Legal System, Coursework - Essay Example The main feature of the English legal system is that it is living and constantly evolving to work in the future as well as it did in the past1. Thus the single most unique feature of the English legal system is its inheritance from common law2. Most of the characteristics commonly linked to English law and its management of righteousness are traceable to the early on growth in Western Europe of the civil and common law customs. According to Goodman (1995), "several characteristic consequences flow from the fact that law did not emanate from one centralised authority such as papacy, king or parliament. The odd growth of the common law in England developed it appears from a coincidence resemblance of the implementation after the Norman take-over by consecutive monarchs of native customs as the foundation for the governance of justice. Conflict assessment, chiefly concerning land title, was a key function for justice. Judges were nominated by the king to tour the country and decide controversies, aided by a local adjudicator included by the Normans into operational royal courts. The trial accepted a key role in the settlement of disputes. Wilson (1995) states that "Everyone takes for granted the fact that law and legal systems differ in different countries. But it is also true of legal scholarship. One reason for this is the different responsibilities legal scholars have in different countries for the maintenance and development of the local law...One result is that legal scholars in different countries may have different agendas and this may affect the subject matter, scope and even the form and style of the local legal scholarship." (Source: http://www.chriswallis.com/uni/cnlaw231l01.pdf accessed on November 5 2009). To bring about a faith to the law the courts followed the principle of stare Decisis.3 This is referred to as the doctrine of precedent. The courts are divided into two (IALS Conference, Learning from Each Other: Enriching the Law School Curriculum in an Interrelated World). They are: i. Superior courts; ii. Inferior courts. The House of Lords is the superior court but it is a UK court since it practices appellate authority for all the three legal systems.4 The Superior Courts are known as the Supreme Court from November 2009. The Supreme Court consists of the High Court, the Crown Court and the Court of Appeal (IALS Conference, Learning from Each Other: Enriching the Law School Curriculum in an Interrelated World). The doctrine of precedent's role in the English legal system is very important since common law is a vital basis of law in the English legal system. This is opposite to the European legal system as it is founded on legal examples and possibilities. A lot of stages of study have to be conducted under a common law jurisdiction so that it can be understood as to what the law is. The facts of the law have to be understood first and then any relevant statutes or legal cases have to be located. Finally the principles 3. Meaning "let the decision stand". 4. However the jurisdiction is not universal. For example, whilst there is a right of appeal to the House of Lords against civil actions in Scotland no such right exists for criminal matters. and the decisions used in the case are used for the future
Tuesday, November 19, 2019
Analysis of a manager's job Essay Example | Topics and Well Written Essays - 1000 words - 1
Analysis of a manager's job - Essay Example It is, he said, the series of activities related to the use of available resources to achieve a goal. The resources can be material or human, other people, inside or outside an organization of humans, which a ââ¬Ëmanagerâ⬠has to ââ¬Ëmanageââ¬â¢ or learn how to ââ¬Å"useâ⬠properly to achieve a specific purpose. In his case, he manages the people who work with him: the wait staff, the cooks and kitchen assistants. He includes the customers, not all of whom are pleasant to be with. He also has to manage or ââ¬Ëuseââ¬â¢ resources like the raw ingredients that go into every meal, the drinks they serve, and the place itself. The first function is planning, which involves setting goals and thinking clearly of how those goals can be reached with the people and resources he has. Peter sits down with the owner regularly to discuss profit targets, and he goes over the different ways those targets could be met. He specifies how many people he needs, especially on special days when there are big celebrations or a festival when they foresee many customers coming in to the restaurant. This function includes making a budget, specifying what types of people he should hire, how many of each (cooks, waiters, receptionists, kitchen assistants, and sometimes, valet parking attendants) to hire and the salaries he could give them. He also plans the menu with the cook and the owner, and they find ways to get good quality ingredients that do not cost too much. He often sits down and thinks hard to understand the goal (prepare a birthday dinner for a group of twenty). He asks questions like: do I have enough people, resources, and time; and how do I distribute the work (more so when the cook calls in sick on what could be a busy night)? How can we work together, with the limitations we have, so that we meet the goal on time? These are not easy things to do, especially as he has to plan what to do if any
Sunday, November 17, 2019
Regulating Violent Video Games Essay Example for Free
Regulating Violent Video Games Essay An African proverb says, It takes a village to raise a child. But in this society the child barely has a mother or father to truly depend on. When I was I child I was fortunate to have a family so close that if I did something wrong, it seemed like the whole world knew. This is what made me the human being I am today. My philosophy is somewhat like a doctorââ¬â¢s oath, ââ¬Å"First do no harmâ⬠. With this idea I believe in karma what you send out will come back to you. ââ¬Å"Hate begets hate; violence begets violence; toughness begets a greater toughness. We must meet the forces of hate with the power of love. (Martin Luther King, 1958) So whose place is it to deal with the problem of violence in video games? The problem is ours because we have the caused the demand for such games. And without the demand there would be no need for them. But since we do have them just as we have guns, the parents should take back control. Just as you donââ¬â¢t allow your children to listen to offensive rap music, or play with guns. The same way you donââ¬â¢t want your child to look at pornographic material we should censor the games our children play. Why is this, the parentââ¬â¢s problem? Well you did bring them into this world, and are therefore responsible for their well-being including their mental growth. When a child plays violent games, studies show that their brain is stimulated. But donââ¬â¢t books do the same thing. Being a parent means you live by example and even if you canââ¬â¢t do that you should make the right choice for youââ¬â¢re under age child. By allowing such games to be played, this tells the child that it accepted. Imagine a child that watches porn all day long and no one could possibly think that one day he will be a sexual deviant. Of course when asked why he turned out this way, he will say it was the porn. But what of the parents that let him watch said porn. Shouldnââ¬â¢t the parents be the ones to be held responsible? I guess once its reached that point that would be crying over spilt milk. So start now, while they are young and pliable. Teach that violence is not laughable in real life or a game. Our county was based and founded on the freedoms that have allowed our country to be great. The freedom to exist, to pursue happiness if we so choose. We have freedom of speech, expression and even non-expression taking our liberties one day at a time. So could playing video games and watching violent movies be a form of expression. And if it is considered a form of expression, I believe that the government should not have a part in the regulating of such things. Except to provide information of the dangers it could cause. Like smoking cigarettes and drinking alcohol; donââ¬â¢t restrict me by taking my choice away but help me to better understand the consequences of my choices. If the government did more than just put ratings on video games, like banning them like banning ââ¬Å"2 Live Crewâ⬠; it would cause an outrage from the country. People who donââ¬â¢t even play video games would wake up and find the error in such banning. This banning would be a form of taking away an Americans rights. Because after all even though we have a black president, we are not so far ahead of times to misunderstand the banning as a form of protection. But believe that we would somehow become a communist state over night. Somehow the liberties we take for granted would become the reason people would fight for the wrongness of such violent images. We should as a nation take responsibility for our actions and our childrenââ¬â¢s actions. If we did this there would be no need for the government to regulate our lives in such ways as banning the things that allow for self expression. And even though violence may or may not touch our lives sometimes daily there is no reason keep those that like the blood and guts from their idea a fun. If you not portraying the serial killer you are watching or playing there is no need for my concern or the governmentââ¬â¢s regulation on such matters. In conclusion, I am against violent video games but I understand the need for others to participate in such activities. I also understand that taking away such rights to play these games would cause chain reaction of government control of not only what is played but viewed and voiced. I believe if we are able to have full knowledge of the things we bring home, and then maybe we wouldnââ¬â¢t bring them home. But if we do then we are prepared for the consequences. In being prepared we teach our children not only what is right and wrong, teaching to them to be aware of what they are teaching themselves. If parents monitor what their children do, watch and play, maybe the question of regulating violent video games would not be a question. Because it should be the parents who regulate and teach the children what is real. By teaching the children what is meant for entertainment? To teach the children to never let the games they play become their reality.
Thursday, November 14, 2019
The Roots Of Blues Music :: essays research papers
The Roots of Blues Music Blues is a very important type of music. Most music that you hear today has some form of blues in it. If it wasn't for the blues there wouldn't be any rock and roll, country, rap, pop, or jazz . Blues is also important for African American culture. African Americans were also the people who started the blues. The Blues started in the late 1800's in levee camps or plantations in places like Mississippi, Louisiana, and Texas were many African Americans lived. The blues of that time was called country blues. It was a mixture of African music, field hollers, work songs, religious music, and ragtime. The main influence of blues music was African music which has a strong and steady beat using drums or other instruments. Its beat and singing showed in the blues. Work songs and field hollers were an influence on blues. They were mostly made up as the musicians were singing. They were a mixture of story telling and talking with a definite call and response. Religious music was very important in forming blues music. Because most blacks went to Christian churches from an early age and were exposed to Christian hymns. Ragtime was an influence that came later and is a faster blues played with the piano and someone singing which was usually played in bars called barrel houses. The first country blues that was written and published was "Memphis Blues" by W.C. Handy in the early 1900's. The first recorded blues was " Crazy Blues" by Mamie Smith in 1915. Most country blues were played with an acoustic guitar and with someone singing. It also has a definite call and response between the voice and guitar. Guitars were used because they had a broad range of notes, they were portable, affordable, and they were permitted by slave owners at that time. The slave owners didn't permit drums because they thought the drums could be used to signal to each other. There were many beginning Blues musicians but only a few had their songs written, published, or recorded. The Roots Of Blues Music :: essays research papers The Roots of Blues Music Blues is a very important type of music. Most music that you hear today has some form of blues in it. If it wasn't for the blues there wouldn't be any rock and roll, country, rap, pop, or jazz . Blues is also important for African American culture. African Americans were also the people who started the blues. The Blues started in the late 1800's in levee camps or plantations in places like Mississippi, Louisiana, and Texas were many African Americans lived. The blues of that time was called country blues. It was a mixture of African music, field hollers, work songs, religious music, and ragtime. The main influence of blues music was African music which has a strong and steady beat using drums or other instruments. Its beat and singing showed in the blues. Work songs and field hollers were an influence on blues. They were mostly made up as the musicians were singing. They were a mixture of story telling and talking with a definite call and response. Religious music was very important in forming blues music. Because most blacks went to Christian churches from an early age and were exposed to Christian hymns. Ragtime was an influence that came later and is a faster blues played with the piano and someone singing which was usually played in bars called barrel houses. The first country blues that was written and published was "Memphis Blues" by W.C. Handy in the early 1900's. The first recorded blues was " Crazy Blues" by Mamie Smith in 1915. Most country blues were played with an acoustic guitar and with someone singing. It also has a definite call and response between the voice and guitar. Guitars were used because they had a broad range of notes, they were portable, affordable, and they were permitted by slave owners at that time. The slave owners didn't permit drums because they thought the drums could be used to signal to each other. There were many beginning Blues musicians but only a few had their songs written, published, or recorded.
Tuesday, November 12, 2019
The Company of Wolves
ââ¬Å"The Company of Wolvesâ⬠by Angela Carter follows the story line of the classic childrenââ¬â¢s fairytale ââ¬Å"Little Red Riding Hoodâ⬠which is known universally in the western world. Despite the relationship between the two stories, ââ¬Å"The Company of Wolvesâ⬠has cunningly been written with an eerie atmosphere and plot twists to engage the reader. Reinvented into a gothic fantasy, the story highlights Red Riding Hoodââ¬â¢s innocence and uses the Wolf as a metaphor for men to position the reader to react differently than the classic fairytale.It becomes obvious to the reader that the story is based upon the well known fairy tale ââ¬ËLittle Red Riding Hoodââ¬â¢ but Carter has twisted the innocent childrenââ¬â¢s story into a extravagant gothic fantasy which positions the reader to grasp a greater understanding of the events leading up to the climax and the background in general. The stylist choices of magic realism differ from the classic denot ation of fantasy because realistic frameworks of the real world are twisted with the supernatural resulting in murderous, sadistic or brutal situations; in this instance Red Riding Hood engaging in sexual acts with the Wolf.From the beginning the reader is fully aware of the stylistic choice of gothic fantasy, ââ¬Å"One beast and only one beast howls in the woods by nightâ⬠is typical of gothic tales as woods are usually portrayed as a dangerous and a forbidding setting, but also provides emphasis through repetition of ââ¬Ëone beastââ¬â¢ and ââ¬Ëonly oneââ¬â¢ to draw the readerââ¬â¢s attention onto the fact that the Wolf is important and plays a significant role in the story.A common aspect of gothic tales is winter which is the setting of the story, as shown through distribution of the words ââ¬Ësnowââ¬â¢, ââ¬ËChristmasââ¬â¢, ââ¬ËRobinââ¬â¢, ââ¬Ëblizzardââ¬â¢ and ââ¬Ëcoldââ¬â¢ throughout the story which are classic connotations rel ative to the season. The stylistic choice made by Carter in relation to the classic fairy style creates an eerie atmosphere and positions the reader to question if they really know the plot of the story.Little Red Riding Hood is portrayed as an innocent little girl in the classic fairy tale which is carried through into Carters version with a few twists. Initially Little Redââ¬â¢s innocence is clearly defined as her virginal status is described using metaphors as ââ¬ËShe is an unbroken egg; she is a sealed vesselââ¬â¢ and her physical appearance resembles that of a young girl ââ¬Ëhair like lint, pale forehead, scarlet cheeksââ¬â¢. Since she has ââ¬Ëstarted her womanââ¬â¢s bleedingââ¬â¢ it is safe to assume that her shawl is symbolic to represents just that or her innocence as she nters this period of her life. As the story progresses Little Red does not hesitate to hand over her basket when ââ¬Ëhe [the Wolf] offered to carry her basketââ¬â¢, assuming th e basket is a symbol used to represents her virginity this scene illustrates how uneducated girls in this era were about sex and the risk it posed to them. Little Red is not hesitant about handing over her basket because she has no clue about what the Wolf is doing, although she does not know what was about to happen to her he certainly does.At this specific point in the story the reader is positioned to re-evaluate the innocence of the girl, questioning whether the wolf is taking advantage of her or whether she knows what she wants. Regarding Little Redââ¬â¢s shawl representing her innocence, nearing the end of the story the Wolf exclaims in reply to her asking what to do with it choice of diction, ââ¬Å"Throw it into the fire, dear one.You wonââ¬â¢t need it again,â⬠clearly distinguishes that he has taken her innocence and virginity and that there is no way for it to be reversed; ââ¬Ëfireââ¬â¢ representing an irreversible doing. The innocence of Little Red has in evitably been taken away and no long exists to the reader, the reader will no longer be able to read the original version without the constant reminder of Little Redââ¬â¢s deterioration of innocence in Carters version. Carter, being a classic feminist, has shaped the Wolf into a metaphor of the negative side to men.To begin ââ¬ËOne beast and only one beast howls in the woodsââ¬â¢, in particularly the repetition of ââ¬Ëoneââ¬â¢ and ââ¬Ëonly oneââ¬â¢ provides emphasis upon the fact that there is only one wolf and that he is an important asset to the story, perhaps the fact that the story could not function without this male character which makes him very important and dominant. Carter has used this to mirror her opinion that men, or some men, have a mindset that a womenââ¬â¢s life could not function without them. The wolf is quick to ââ¬Ëoffer[ered] to carry her basketââ¬â¢, which is a symbol of her virginity.These actions demonstrate Carters opinion on m en thinking they can dominate women especially since the Wolf knew exactly what he was doing relative to Little Red who was oblivious to his actions because she is uneducated on sex. The Wolf is conveyed by the reader as a vicious sexual predator out to claim young girlââ¬â¢s virginity, which positions them to feel sympathetic for Little Red who represents women. The dominancy of the Wolf taking the girls virginity is pursued near the end of the story as the Wolf orders her to, ââ¬Å"Throw it [shawl] on the fire, dear one.You wonââ¬â¢t need it again,â⬠which is significant because the shawl represents her virginity which has now been burnt. The diction of the phrase ââ¬Ëdear oneââ¬â¢ is effective because it demonstrates how a man can pretend to care about a girls feelings and be sweet in order to manipulate her into doing something to his advantage. By this point in the story the reader has been positioned to view the Wolf differently from the one that gets killed in the traditional story to a dominant male character who has no respect for Little Red.Once the reader has read ââ¬Å"The Company of Wolvesâ⬠they definitely wonââ¬â¢t be able to see the classic ââ¬Å"Little Red Riding Hoodâ⬠in the same light again. Reinvented into a gothic fantasy, the story highlights Red Riding Hoodââ¬â¢s innocence and uses the Wolf as a metaphor for men to position the reader to react differently than the classic fairytale. The story however does not necessarily have only negative outcomes because it could make the reader to think deeper about how other characters in different fairytales have been portrayed and how they can challenge the expectations they have been placed in.
Sunday, November 10, 2019
Latitude and Type Your Response
Mapping The Lesson Activities will help you meet these educational goals: Science Inquiry? You will conduct online research, collect information, and communicate your findings In written form. STEM?You will apply scientific tools and knowledge to solve real- world problems in order to grow in your understanding of science as a creative human activity. 21st Century Skills?You will employ online tools for research and analysis, use critical thinking and problem-solving skills, and communicate effectively in order to solve real-world problems. DirectionsWrite a response for each of the following activities. When you have finished, submit your work to your teacher. Check the rubric at the end of this document to make sure your work is meeting the expected criteria. Task 1: Coaching In adventure books and movies, the hero sometimes has to follow a map to find a burled treasure. Today, a new sort of adventure sport has become popular In which people use technology to ââ¬Å"findâ⬠tre asures. Coaching involves global positioning satellites, maps, and participants' sense of adventure to locate specific geographic spots.These could be situated in a local area and tracked down In ââ¬Å"real timeâ⬠or located anywhere on Earth and identified virtually. As you know. Every point on Earth can be Identified by latitude and longitude. In this lesson, you studied how to read points on a map in degrees, minutes, and seconds of latitude and longitude. For example, the Space Needle in Seattle, Washington, is located at approximately 470 37â⬠² 14â⬠³ N. 1220 20â⬠² 57â⬠³ W. Use your map reading, Internet searching, and reasoning skills to find the following locations and answer the three questions for each.
Thursday, November 7, 2019
Summary of Carrie Essays - Carrie, Rita Desjardin, Sue Snell
Summary of Carrie Essays - Carrie, Rita Desjardin, Sue Snell Summary of Carrie English Summary. A Summary of Carrie. So far they have brought you into the beginning of how it all started. Carrie just had her first period at the age of seventeen and they tell you about how people bully her and who is on top and who is not. They brought a lot of characters into light like Sue, Chris and Ms. Desjardin, and a little on who they may become as the story goes along. The story shows you how evil Carrie?s mother is and how Carrie has been treated at home as a little child to a teenager. Carrie?s is also using her powers to hurt and to scare like when she makes a kid fall off his bike or when she tells her mom she will make the rocks come back. A Paraphrase On page 49 about half way down, Sue and her boyfriend Tommy are talking about the past when Tommy kicked a kid while he was down and how Sue feels bad about what she said. In the passage, what I got from it was that Sue feels bad for what she did to Carrie and wants some reason to apologize to her. Tommy tells his story to her and states that he did not apologize for what he did because he had a good reason to do it. He also tells Sue that she did not have a good reason for doing what she did because Carrie never did anything to her.
Tuesday, November 5, 2019
Take this quiz to find out what your most dominant work trait
Take this quiz to find out what your most dominant work trait You have several traits that are excellent for work; such as being hardworking, dedicated, loyalâ⬠¦ The list goes on and on. But have you ever wondered what your most dominate trait in work is? Itââ¬â¢s so hard to just pick one thatââ¬â¢s why this quiz is perfect for helping you decide.à Source [Playbuzz]
Sunday, November 3, 2019
Contemporary issues in business Essay Example | Topics and Well Written Essays - 2500 words
Contemporary issues in business - Essay Example Being headquartered in United Kingdom, it serves the customers in the market of United Kingdom efficiently. As a result of which, the brand image and profitability of the financial organization of Lloyd's bank enhanced with a significant extent thereby amplifying its popularity. Along with this, due to the presence of varied types of products such as insurance schemes, deposit schemes and many others, its range of customers and brand value enhanced thereby amplifying its popularity and reputation in the market of United Kingdom among many other rival players. And so, the demand and total revenue of the financial organization of Lloyd's bank enhanced by ?19,673 million resulting in reduction of the threat of new entrants. Apart from this, due to the presence of value-added services, it expanded in more than 30 countries, from Argentina to United States of America, comprising of approximately 16 million employees. This acted as the prime cause that helped the organization of Lloyd's ba nk to amplify its profitability by ?2,803 million and market size by 6% in the market of United Kingdom among others (Lloyds Bank, 2013). Therefore, in-spite of tough competition and stiff economic downturn, the organization of Lloyd's bank maintained its sustainability in the market of United Kingdom among many other rival players. This essay is mainly divided into five parts highlighting the importance and background of Lloydââ¬â¢s bank in the market of United Kingdom. Along with this, it also discusses the impacts of contemporary issues over the image and popularity of the organization of Lloyd's bank. Moreover, it also discusses the negative effects of the contemporary issue of unethical use of labor or staffs within the financial organization of Lloyd are thereby enhancing the rate of switchover costs. 2. Discussion 2.0 Drivers of Change (PESTLE) In order to analyze the external environment, competitors and market opportunities of Lloydââ¬â¢s bank, the most popular analyt ical tool named PESTLE is used. 2.1 Political- As, the political scenario within the regions of United Kingdom, Europe and America is extremely stable, so it proved quite beneficial for the organization of Lloydââ¬â¢s bank among others rival players. As a result of which, the profitability and brand value of the organization of Lloydââ¬â¢s bank enhanced thereby amplifying its range of customers. It is extremely essential for any organization to retain its portfolio in the market, in-spite of numerous existing contenders ( Xu, 2005, pp. 478-536). 2.2 Economic- Global inflation acted as a curse for the organization of Lloydââ¬â¢s bank thereby reducing its effectiveness to a significant extent. This is mainly because; inflation enhanced the level of unemployment and poverty thereby reducing the preference for depositing huge-amount of revenues within the financial institutions. Along with this, the consumer price index (CPI) also reduced by 3.5% that proved extremely worse for the country of United Kingdom. As a result of which, the living standard and life style of the citizens of United Kingdo
Friday, November 1, 2019
Internet TV Assignment Example | Topics and Well Written Essays - 1000 words
Internet TV - Assignment Example At the same time, it will save huge cost of the viewers. The companyââ¬â¢s aim is to deliver news instantly across its network so that it reaches the customer on demand and at the same time faster than its competitors. The internet TV model will help the company achieve this goal. In the traditional TV model, the broad casting station had to depend on the cable operator for transmitting their news to viewers. Now, this model had limitation that some cable operator might charge extra money to viewers to watch the channel which often acted as a barrier between the company and target audience. With the new O-T-T model, the company will be able to reach their customers directly through internet. The broadcasting network will receive payments from the customers directly by shifting to the new model, as it eliminates the cable operator from the picture. Such model is beneficial for both the NBC as well as its viewers as the company will be able to receive new streams of revenues that we re blocked with cable operators in the earlier model (Odlyzko, 2001, p.8). In short we can say that there will no net losers for the new model since the viewers will pay less since they are paying directly to broadcasting station and the NBC will receive greater revenues since it does not have to share its revenues with the cable operators. Action Plan for Rogers Rogers Communications Inc. is a diversified Canadian telecommunication company. The company broadcasts its network across various media including the television, radio, internet, etc. If we consider the traditional TV model which the company used to reach their customer, we will find that the model has limited scope for transmission if the company wants to be global. This is mainly because when domestic company plans to operate globally, it has to take many clearances from the promotional boards. At the same time, it will need local distribution networks. Thus, we can say that the entire process is complex as well as techni cally costly to implement that way. The company has the option to opt the O-T-T TV model that will enable the global viewers, thanks to the application of e-commerce industry. This model does not need local distributors, or foreign clearances. All a customer needs to see their favorite channel is to connect their television with internet using a set-top box. Thus, if Rogers implement this model, their organization will definitely have competitive advantage as well as cost advantage. At the same time, large number of viewers across the globe may be targeted without any troubles. The model is very simple and easy to implement. In short, we may say that Rogers as well as its TV viewers will be gainers if this model is implemented by the organization. Action plan for Bell Canada Bell Canada is a Canadian telecommunication and media company. The companyââ¬â¢s main competitor is Rogers. With both the companyââ¬â¢s working in same line of business, the company that will reach its vie wers faster and smarter way will be the gainer. If Bell adapts the O-T-T model, it will significantly reduce its cost of transmission as they will not have to share their revenues with the middle-men or the cable
Wednesday, October 30, 2019
BarChris Construction Case Study Example | Topics and Well Written Essays - 250 words
BarChris Construction - Case Study Example The misappropriated entries included current assets having a 15% overstatement of $609,689; 42% understatement in contingent liabilities amounting to $618,853; gross profit overstatement of $230,755; $519,810 worth of salesââ¬â¢ overstatement; undisclosed loans to officers totaling to $386,615; and an overstatement in backlog of orders among other figures. Auditing involves the application of accounting principles as they relate to costs and revenues. Following the sale and leaseback cases, the judgeââ¬â¢s argument that the gain on the debentures was improper is misleading since this approach is accepted in GAAP. Although the customers who acquired the leaseback properties incurred overwhelming arrears on their discounted notes, it is not considered a reasonable standard for auditors to concern themselves with the effects of business strategies of the companies they audit. Hence, as earlier stated, the auditorsââ¬â¢ responsibility is to access, point, question, and report on accounting activities and not on investment or business strategies associated with the gains (United States District Court, 1968). The case of Berardi places himself at the center of blame for the problems associated with BarChartââ¬â¢s accounting misappropriations. The merits of blaming Berardi for the problems facing BarChris include his inability to dedicate more time to review the results of the S-1 review, the hiring of an inexperienced accountant, and concealing of information such as loans to officers. In order to rectify these causes of the primary problems, Berardi could have hired a qualified accountant, should have dedicated more time to review accounts, and conducted regular internal audits (United States District Court, 1968). United States District Court. (1968). Escott v. Barchris Construction Corporation 283 F. Supp. 643 (S.D.N.Y. 1968). Accessed online on February
Sunday, October 27, 2019
Gluconeogenesis: Fructose 1, 6 Bisphosphatase Deficiency
Gluconeogenesis: Fructose 1, 6 Bisphosphatase Deficiency Ashley Woodin Introduction Fructose-1, 6-bisphosphate is a key regulatory step in gluconeogenesis, as well as many other intracellular metabolic pathways. During gluconeogenesis there is an important process in which there is a conversion of glucose to pyruvate which is known as glycolysis. This process will require three irreversible steps that have a very high negative free energy that is in the forward reaction. So, in order to have a conversion from pyruvate into glucose, the pathway will require the use of enzymes, which will allow the bypassing of these irreversible steps. One of the enzymes that is used in this process is called Fructose 1, 6-bisphosphatase (Kelley, 2006). This step is a very important step in gluconeogenesis, being that it needs to have fructose bisphosphatase to catalyze the conversion of fructose-1, 6-bisphosphate into fructose 6-phospahate, and inorganic phosphate, that without it can block the pathway. Its activity is high regulated by the levels of Adenosine Monophosphate, fructos e 2, 6-bisphosphate and also citrate (Kelley, 2006). When deficiencies are present in this pathway and devoid of this conversion, glycerol into glucose, it will lead to fasting hypoglycemia, lactic acidosis and other physiological conditions. This enzyme is highly active within the liver and the intestines. Therefore, when the liver glycogen stores are no longer available, the physical properties of the body will fight for its homeostasis (Eren, 2013) by converting a three carbon based molecule such as non-carbohydrate precursors, like lactate, glycerol as well as pyruvate, in order to maintain blood glucose levels (Eren, 2013). There is a physiological change in the body there is a need for glucose to be synthesized. When there is a high demand upon glucose synthesizes, the gluconeogenic pathway is increased exponentially. This demand typically occurs during high cardio, pregnancy and lactation (Wallace, 2002). There can also be an increase demand upon gluconeogenesis when the body is in a fasting state (Wallace,2002). Hypoglycemia has a high dependence upon gluconeogenesis formation, because it is the key metabolic pathway which will protect this physiological problem. Moreover, hypoglycemia is a very life-threating situation. Within the gluconeogenesis metabolic pathway, Fructose 1, 6-bisphosphatase is very crucial; as it aids in biochemical reactions and many of the physiological functions of the body. Structure and Properties Fructose 1,6-bisphosphate with six carbon sugar molecules is also known as the Harden-young ester, it has fructose sugars which are phosphorylated on the C1 and C6 (Diwan, 2006). However, before this step can be achieved it needs to start from the beginning in gluconeogenesis. It is important to note that glycolysis and gluconeogenesis are not reversed pathways. Itââ¬â¢s clear to see that glycolysis and gluconeogenesis will have a lot of the same enzymes embedded within each other; however these two functional pathways are not the reverse of each other. Moreover, the irreversible steps, that are high exergonic, in glycolysis are bypassed in the gluconeogenesis pathway (Berg JM, 2002). In fact, each of the pathways is so tightly controlled by the intercellular as well as the intracellular signals, and they are highly regulated so that glycolysis and gluconeogenesis will not occur in the same cell at the same time (Berg JM, 2002). Looking at the glyconeogenic pathway the ability to see that there is a conversion of pyruvate into glucose (Berg JM, 2002). These conversions are achieved by Non-carbohydrate precursors of glucose, in which they are either first being converted into pyruvate, or they will enter the pathway at later pathway intermediates like oxaloacetate and dihydroxyacetone phosphate . There are currently three major non-carbohydrate precursors that are looked at, and they are lactate, amino acids, and glycerol. The first (1) precursor stated above is lactate, it has a formation that is by the active skeletal muscle, this occurs at a when the rate of glycolysis has reach its maximum of the oxidative metabolism (Berg JM, 2002). The amino acids with a carbon skeleton (Brandt, 2003) are derived from the amount of proteins that are in the diet, as well as starvation, from the breaking down of the proteins that are housed within the skeletal muscle (Berg JM, 2002). Lastly, the glycerol will obtain fat cells by the hydrolysis of triacylglycerols which wi ll yield glycerol as well as the lipids (Berg JM, 2002). As stated above, before looking at fructose-1,6-bisphosphate the beginning steps in gluconeogenesis needs to be looked at. Biosynthesis. We began synthesis by looking at the glycolysis pathway, there are a lot of enzymes that are used to synthesize glucose from a pyruvate stage. There are three reactions in glycolysis which we termed irreversible (specifically those catalyzed by pyruvate kinase, phosphofructokinase, and hexokinase) are not used in gluconeogenesis synthesis (Selinsky, 2002). These three (3) reactions of Glycolysis have such a large negative delta G in the forward direction that they are essentially irreversible, which is why bypass is used by enzymes in order for them to be synthesize. The delta G will make a determination of the proper direction of the carbon flow through the pathway (Brandt, 2003). Gluconeogenesis needs to be more exergonic, so in order to make that happened six ATPs are consumed (Miles, 2003).The first step or bypass, is by converting 3 carbon pyruvate into 4 carbon intermediate oxaloacetate , biotin-requiring reaction catalyzed (King, 2014), this is called pyruvate carboxylate (Sel insky, 2002). This mitochondrial enzyme will convert the pyruvate into oxaloacetate. Pyruvate carboxylase is a mitochondrial. The biotin is interconnected heavily as it is bound to the amino group covalently on the lysine side chain of the pyruvate carboxylase (Brandt, 2003).à Pyruvate carboxylase catalyzes formation between the biotin (Biotin has a 5-carbon side chain whose terminal carboxyl is in an amide linkage to the e-amino group of a lysine of the enzyme (Diwan, 2007)), and carbon dioxide carbonate by having a covalent bond. When there is a reaction that is ATP- dependent, the carbonate will then be put into action and transferred to the pyruvate substrate, in order to make a molecule oxaloacetate (Brandt, 2003). the high and low amount of concentration of acetyl CoA and ATP will ultimately decide is the oxaloacetic acid will survive or diminish (Ophardt, 2003). If there is a lower amount of acetyl- CoA and higher concentrations of ATP than the pathway will continue (Ophardt, 2003). A Transport of oxaloacetate out of mitochondria Oxaloacetate Malate NADH + H + NAD + Malate Oxaloacetate NADH + H + NAD + Inner mito are seen in this first bypass step. The Using a specific enzyme the Oxaloacetate will now be able to be converted into phosphoenolpyruvate , by the enzyme phosphoenolpyruvate carboxykinase (Selenski, 2005). This Mgà ²+ enzyme will require is GTP being the donor for when there is the possibility for a phosphoryl transfer reaction, thus losing the loss of a COà ² molecule. Therefore, within this first step bypass synthesis, the reaction has gone from, phosphoenolpyruvate to pyruvate, and overall one (1) ATP is gained. In returning to phosphoenolpyruvate from pyruvate, the equivalent of 2 ATP must be consumed (Selinsky, 2002). Note that the COà ² that was gained in the pyruvate in the beginning of the pyruvate carboxylase step, has now been loss in the phosphoenolpyruvate carboxykinase. The second (2) bypass Now, to go from phosphoenolpyruvate to fructose-1, 6-bisphosphate into 6-bisphosphate, with this reaction the same reaction can be used, entirely by the concentrations of substrates and products (Selinsky, 2002). Because the reaction being exponentially endergonic, thus irreversible, the transition from the fructose 6-phosphate uses a catalyst from a different Mgà ² + enzyme called the dependent fructose 1, 6-bisphosphatase, (Lehninger, ) This will promote an irreversible hydrolysis at the C-1 phosphate (Lehninger,). This is the third (3) bypass of gluconeogenesis which is the final step and in most tissues gluconeogenesis would end at the fructose 6-phosphate which was generated by fructose 1, 6 bisphosphatase being converted into glucose 6-phosphate. So, basically instead of having free glucose being generated, glucose 6-phosphate would be converted in glycogen ( Tymoczko, 2013). In this final step of gluconeogenesis, free glucose is will take shelter in the liver. Glucose 6-phosphate is then transported into the lumen if the endoplasmic recticulum, thus it is then hydrolyzed to glucose by the glucose 6-phosphatase (Tymoczko, 2013). Note that each of the step reactions that have been achieved, to the formation of glucose from pyruvate is considered energetically unfavorable, unless there are coupling reactions which are favorable (Tymoczko, 2013). In the end of this biosynthesis there are six (6) nucleoside triphosphate molecules that have been hydrolyzed in order to achieved a synthesize of glucose from pyruvate (Tymoczko, 2013). Regulation Gluconeogenesis is highly regulated by a series of regulations. The steps are broken down and now they have to be a regulation in gluconeogenesis. It is obvious that itââ¬â¢s going to have a direct correlation contrast to glycolysis. Consider the first stage in which energy is needed (Tymoczko, 2014). The main site of regulations is seen when the there is a regulation in the activity of PFK-1 and F1,6BPase and this would be the most important site for the controlling of the flux which is toward glucose oxidation or even when there is glucose synthesis. As described in control of glycolysis, this is predominantly controlled by fructose-2,6-bisphosphate, F2,6BP which is a powerful negative allosteric effector of F1,6Bpase activity (King, 2004). ââ¬Å"Acetyl CoA is an allosteric effector of both glycolysis and gluconeogenesis. Acetyl-CoA inhibits pyruvate kinase and reciprocally activates pyruvate carboxylase (Miles,2003). Second, insulin and glucagon are very important when regulating pathway (Wallace,2002). There will be a decline in the response to the glucagon stimulation, when the level of Fructose 2,6 bisphosphate decline in the hepatocytes (King, 2014). Once these signals are stimulated the signals will be excited through an activation of the cAMP-dependent protein kinase (King, 2014). Both the PFK2 and fructose bisphosphatase are present in the 55-kd polypeptide chain (Tymoczko, 2013). here is a substrate enzyme which is bifunctional (King, 2014) which contains a N-terminal regulatory domain (Tymoczko, 2013) being responsible for the synthesis of the hydrolysis of fructose 2, 6- bisphosphate and that is the protein kinase a phosphatase domain. Therefore once the PFK-2 is phosphorylated by PKA it will start to dephosphorlate, by acting as a phosphatase (King, 2014). ââ¬Å"AMP will ultimately enhances the inhibition of Fructose-2,6-BP. Note that these allosteric effectors of fructose-1, 6-bisphosphatase all are allosteric effectors of phosphofructokinase (Miles, 2003). These effectors reciprocally regulate both enzymes. Furthermore, fructose 1, 6-bisphosphase once itââ¬â¢s active, its activity will be highly regulated by the ATP to ADP concentration (Tymoczko, 2014). When this is high then gluconeogenesis can proceed to its highest potential. PROKARYOTES VERSUS EUKARYOTES Gluconeogenesis conversion happens in both the eukaryotic and prokaryotes, however it is very important to know its difference. In eukaryotes the lactate that is formed anaerobically within the muscles will be converted to glucose in liver and kidney, thus being stored as glycogen or even being released as blood glucose (Davis, 2014). In prokaryotes the production of the G3P product of photosynthesis will be converted in a starch form and then further stored in the chloroplasts or even being converted into glucose and sucrose, where it is then exported to the other tissues for starch storage (Davis, 2014). As stated above when it comes to the biosynthesis of all eukaryotes, it is an requirement for survival, because so much of the homeostasis of the body (e.g., the brain and the nervous system),glucose from the blood as the primary fuel source ( Nelson, 2012). Just alone the human brain will require as much as 120 g of glucose with a one day period (Nelson, 2012). When considering eukaryotes gluconeogenesis will primarly occur in the liver and also in the kidney but not much. In prokaryotes the seedlings, will find that it stores the fate and proteins, which are then converted into disaccharide sucrose foe the ability of transport throughout the plant that is developing (Nelson, 2012). ââ¬Å"The glucose and its derivatives are precursors in the synthesis of plant cell walls, nucleotides and coenzymes, and a variety of other essential metabolitesâ⬠(Nelson, 2012). There are many small organisms that are capable to grow on what are plain organic compounds like acetate, lactate, and propionate. They then will convert to glucose by gluconeogenesis (Nelson, 2012). Defects Pathway Although the pathway may be highly regulated, there are still possibilities for defects to occur. As stated in the beginning of this paper fructose 1, 6-bisphosphatase is very crucial; as it aids in biochemical reactions and many of the physiological functions of the body. In the mechanism of fructose 1, 6- bisphosphatase, there is the Glu98 which will activate a molecule consisting of water. That water molecule will than attack the phosphorus atom on the 1-phosphate of fructose 1,6-bisphosphate (Kelly, 2006).ââ¬Å"The hydrolysis of a phosphate ester can proceed through an intermediate of metaphosphate (dissociative mechanism) or through a trigonal bipryamidal transition state (associative mechanism)â⬠(Kelly, 2006). Fructose-1,6-bisphosphatase which catalyzes the hydrolysis of D-fructose-1,6-bisphosphate (FBP) to D-fructose-6-phosphate (F6P) and inorganic phosphate (Pi), it is the very key to the eyzamatic process of gluconeogenesis (Sato, 2004). phosphofructokinase is also an important catalyze reaction, because it will catalyze the reverse reaction, ââ¬Å"the phosphorylation of F6P during glycolysis, the unidirectional FBPase regulates the flux of sugar metabolismâ⬠(Sato,2004). Furthermore, the enzymatic block can lead to the high amount of accumulation of gluconeogenic precursors (e.g. certain amino acids, lactic acid, and ketoacids) (Kelley, 2006). Therefore, when there is a fructose 1,6 bisphosphatase deficiency is an inherited as an autosomal recessive disorder and a person would have what is called a severe lactic acidosis and also with a diagnose of hypoglycemia. Disease Population in the United States In the United States alone about 10 percent of this nations population is diagnosed with hypoglycemia, from the defect in the enzyme fructose 1, 6, bisphosphatase. This disease affects those who are typically obese and or have type 2 diabetes. In order to try and control the diseas population treatments are use, like Metformin. Metformin is an anti-hyperglycemic reagent that has been used in the patients for over the past several years, in obese patients or overweight patients whose blood glucose levels cannot be controlled non-pharmacologically (Salpeter, 2010). ââ¬Å"Fructose 1,6-BPase is a target for the development of drugs in the treatment of non-insulin dependent diabetes, which afflicts over 15 million people in the United Statesâ⬠(Kelley, 2006). Today it is still unknown on how fructose-1, 6 bisphosphatase is genetically inherited, there are still ongoing studies. Some of the ongoing studies that were seen is if Reye syndrome and sudden infant death, have a direct correlation to a defect in this enzyme, however the research still continues. As stated above, the primary target for hypoglycemia is still heavily looked upon in the obese community, and overweight community, because they are more susceptible to getting diabetes. As see fructose 1, 6 bisphosphatase is the key precursor for the gluconeogenesis pathway to occur. It is very important that the sugar intake is watch closely, when children are at a young age. According to a recent study, it is shown that fructose intolerant is seen in late infancy stage and only after they have a dietary ingestion of foods that are containing fructose or sucrose. Foods such as such as fruits, juices are the primary transportantion. The organs commonly affected by fructose bisphosphatase deficiency are liver, kidney cortex and intestinal mucos (Frazier, 2013). Overall Pathway of Gluconeogenesis Now, putting the metabolic pathway all together, Conclusion Fructose 1, 6 bisphosphatase is a very crucial enzyme to the continuance of gluconeogenesis regulation. With the literature that has been conducted, it lays out step by step why this metabolic biosynthesis pathway is vital to eukaryotic and prokaryotic. There are ways to combat this disease, and that is by maintaining a healthy diet. This entail will work to defeat the affects that this has on the population. BIBLIOGRAPHY Brandt, M. Amino Acid Breakdown. 2003. Retrieved from https://www.rose-hulman.edu/~brandt/Chem330/Amino_acid_breakdown.pdf. (Accessed December 5, 2014). Berg JM, Tymoczko JL, Stryer L. Biochemistry. 5th edition. New York: W H Freeman; 2002. Chapter 16, Glycolysis and Gluconeogenesis. Diwan, J. Gluconeogenesis: Regulation of Glycolysis Gluconeogenesis. Retrieved from http://www.rpi.edu/dept/bcbp/molbiochem/MBWeb/mb1/part2/gluconeo.htm#intro. (Accessed December 5, 2014). Frazier D. Glycogen Storage Disease Laboratory. 2013. Retrieved from http://pediatrics.duke.edu/divisions/medical-genetics/biochemical-genetics-laboratory/glycogen-storage-disease-laboratory/tes-8. (accessed on December 5, 2014) 2014). King, M. Gluconeogenesis: Endogenous Glucose Synthesis. 2014. Retrieved from http://themedicalbiochemistrypage.org/gluconeogenesis.php#. (Accessed December 5, 2014). Kelley, M. Fructose 1-6 Bisphosphatase. Retrieved from http://faculty.uca.edu/mkelley/4121 Web pages/Student_Webpages_2006/Aanu ogunbanjo web things/The webbie.html. (Accessed December 5, 2014). UC Davis. 2013. Gluconeogenesis. Retrieved from http://www-plb.ucdavis.edu/courses/bis/105/lectures/Gluconeogenesis.pdf. (Accessed December 5, 2014). Lehniger, Nelson, and Cox. Principles of Biochemistry. 2002. Retrieved from http://www.irb.hr/users/precali/Znanost.o.Moru/Biokemija/Literatura/Lehninger Principles of Biochemistry, Fourth Edition David L. Nelson, Michael M. Cox.pdf. (accessed on December 5, 2014). Miles, B. Gluconeogenesis. 2003. Retrieved from https://www.tamu.edu/faculty/bmiles/lectures/gluconeogenesis.pdf. (Accessed December 5, 2014). Ophart, C. Glycogenesis, Glycogenolysis, and Gluconeogenesis. 2003. Retrieved from http://www.elmhurst.edu/~chm/vchembook/604glycogenesis.html. (Accessed December 5, 2014). Selinsky, B. Biosynthesis: Gluconeogenesis. 2005. Retrieved from http://www22.homepage.villanova.edu/barry.selinsky/CHM%204622/Carbohydrate%20II%20M16%2005.pdf. (Accessed December 5, 2014). Salpeter SR. Risk of fatal and nonfatal lactic acidosis with metformin use in type 2 diabetes mellitus. Retrieved from http://www.bibliotecacochrane.com/pdf/CD002967.pdf. (Accessed December 5, 2014). Wallace C., Barritt G. Gluconeogenesis. 2002. Encyclopedia of life sciences: p:1-8. (Accessed December 5, 2014).
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